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Role of the pathologist in the differential diagnosis of malabsorption

Journal Volume 69 - 2006
Issue Fasc.1 - Symposium
Author(s) C. Sempoux
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Department of Pathology, Cliniques Universitaires St-Luc, Brussels, Belgium.

Histological examination of small intestinal biopsies is an essen- tial step in the assessment of malabsorption syndromes. Multiples biopsies should be taken in the proximal jejunum or distal duo- denum and correctly oriented. Histological evaluation has to be systematic considering villous architecture, inflammation and specific diagnostic elements. In celiac disease, even with the development of serology tests, the biopsy remains useful to follow the patient and to detect potential complications. (Acta gastro- enterol. belg., 2006, 69, 49-51).

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